To do what ?
Identification of compound mitochondrial-targeting properties
What kind of assays ?
Mitochondrial targeting/protection
Mitologics developed assays to identify potential mitochondrial target of compounds (ex. Permability Transition Pore, Mito K-ATP channels, Bax/Bak pore, complexes from respiratory chain...). Mitologics proposes assays to detect the protective properties of compounds to protect mitochondria against specific stress (ionic, oxidative, apoptotic...) (Buron et al., PloS One, 2010; Brabant et al., 2009; Belzacq-Casagrande et al., 2009).
PRECLINICAL STUDIES
ONCOLOGY
ORGANOPROTECTION
CARDIOPROTECTION
DRUG DISCOVERIES
CARDIOTOXICITY
HEPATOTOXICITY
DILI
NON TOXIC COMPOUNDS
COMPOUND SAFETY
SLIMMING
ANTI-AGING
TOXICITY PROFILING
CONTAMINANT EFFECTS
MITOCHONDRIA
RESPIRATION
OXIDATIVE STRESS
APOPTOSIS
HEPARG®